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Texas Compassionate Use Program: Qualifying Conditions in 2026

Texas’s Compassionate Use Program covers defined conditions for low-THC cannabis. HB 46 expanded the list effective September 1, 2025; a qualified physician must assess eligibility.

Read this as education.Check the references, verify current laws, and use qualified professionals for personal medical or legal decisions.
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Key takeaways

  • Texas HB 46 took effect September 1, 2025 and expanded TCUP’s qualifying condition categories.
  • The enacted list includes epilepsy, seizure disorder, MS, spasticity, ALS, autism, cancer, incurable neurodegenerative disease, PTSD, a narrowly defined chronic-pain condition, traumatic brain injury, Crohn’s/other IBD, terminal illness or hospice/palliative care, and qualifying research-program conditions.
  • The patient must be a permanent Texas resident and the qualified physician must determine that risk is reasonable in light of potential benefit; do not describe TCUP as an unrestricted card program.
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Texas uses the Compassionate Use Program

Texas calls its medical pathway the Compassionate Use Program (TCUP), which provides low-THC cannabis through participating physicians and the state registry. Texas DPS says HB 46 expanded the program and took effect September 1, 2025. The label "medical marijuana card" can be misleading here; start with DPS's current program legislation page.

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Educational context only; not a personal instruction or guarantee.

Conditions listed in current state law

The enacted HB 46 text lists epilepsy, seizure disorder, multiple sclerosis, spasticity, ALS, autism, cancer, incurable neurodegenerative disease, PTSD, a condition causing chronic pain (which HB 46 defines as severe continuous or intermittent pain lasting more than 90 days, associated with a chronic pathological process, not relieved by specified treatments, and for which THC is viable), traumatic brain injury, Crohn's disease or other inflammatory bowel disease, terminal illness or hospice/palliative care, and conditions approved for a research program when the patient is receiving treatment in it. The law's exact wording controls; see HB 46.

Patient eligibility is more than a diagnosis

The enacted statute requires permanent Texas residency and a physician's certification that includes the diagnosis and a determination that the risk is reasonable in light of potential benefit. The physician and registry process matters; a diagnosis alone does not create a prescription. Read the statute and ask a participating physician about the current application route. See our general medical-card process guide.

Quick FAQ

Did Texas expand its Compassionate Use Program condition list?

Yes. Texas DPS says HB 46 became effective September 1, 2025 and expanded the conditions eligible for low-THC cannabis treatment.

Which condition categories does HB 46 list?

The enacted text lists epilepsy, seizure disorder, MS, spasticity, ALS, autism, cancer, incurable neurodegenerative disease, PTSD, a condition causing chronic pain (HB 46 defines chronic pain as severe continuous or intermittent pain lasting more than 90 days, associated with a chronic pathological process, not relieved by specified treatments, and for which THC is viable), traumatic brain injury, Crohn's disease or other IBD, terminal illness or hospice/palliative care, and qualifying research-program conditions.

Does a diagnosis by itself guarantee a Texas prescription?

No. The patient must be a permanent Texas resident, the physician must meet program rules, and the physician must determine that risk is reasonable in light of potential benefit.

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Cannabis content can become stale when laws, products, or evidence change. Recheck sources and local rules before relying on a guide.